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1

Current status of antimicrobial susceptibility of clinical isolates ofStreptococcus pyogenesin Japan: report of a countrywide surveillance study

Muneki Hotomi, Dewan S. Billal, Jun Shimada, Kazuma Yamauchi, Keiji Fujihara, Noboru Yamanaka, The Surveillance Subcommittee of the Japan Society for Infectious Diseases in Otolaryngology

Journal:

Journal of Infection and Chemotherapy

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

2

Rapid identification of nontypeable and serotype b Haemophilus influenzae from nasopharyngeal secretions by the multiplex PCR

Dewan S. Billal, Muneki Hotomi, Masaki Suzumoto, Kazuma Yamauchi, Intetsu Kobayashi, Keiji Fujihara, Noboru Yamanaka

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

3

Antimicrobial resistance of Haemophilus influenzae isolated from the nasopharynx of Japanese children with acute otitis media

Hotomi, Muneki, Fujihara, Keiji, Sakai, Akihiro, Billal, Dewan S., Shimada, Jun, Suzumoto, Masaki, Yamanaka, Noboru

Journal:

Acta Oto-Laryngologica

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

4

The Current Status of Infectious Diseases in Otorhinolaryngology with Special Emphasis on Acute Otitis Media and Treatment Strategy for Antimicrobial Resistant Pathogens.

YAMANAKA, Noboru, HOTOMI, Muneki

Journal:

Practica Oto-Rhino-Laryngologica

Year:

2000

Language:

english

File:

PDF, 7.23 MB

english, 2000

5

The Effectiveness of Nasal Nebulizer Therapy with Cefmenoxime Hydrochloride and Nasal Drops of Povidone Iodine for Acute Rhinosinusitis in Children

Fujihara, Keiji, Sakai, Akihiro, Hotomi, Muneki, Yamanaka, Noboru

Journal:

Practica Oto-Rhino-Laryngologica

Year:

2004

File:

PDF, 777 KB

2004

6

Treatment and outcome of severe and non-severe acute otitis media

Muneki Hotomi, Noboru Yamanaka, Takao Samukawa, Masaki Suzumot, Akihiro Sakai, Jun Shimada, Yorihiko Ikeda, Howard Faden

Journal:

European Journal of Pediatrics

Year:

2005

Language:

english

File:

PDF, 188 KB

english, 2005

7

Determination of pneumococcal serotypes/genotypes in nasopharyngeal secretions of otitis media children by multiplex PCR

Dewan S. Billal, Muneki Hotomi, Masaki Suzumoto, Kazuma Yamauchi, Jun Arai, Toshiki Katsurahara, Satomi Moriyama, Keiji Fujihara, Noboru Yamanaka

Journal:

European Journal of Pediatrics

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

8

Clinical and microbiological impact of human bocavirus on children with acute otitis media

Levent Bekir Beder, Muneki Hotomi, Masashi Ogami, Kazuma Yamauchi, Jun Shimada, Dewan Sakhawat Billal, Nobuhisa Ishiguro, Noboru Yamanaka

Journal:

European Journal of Pediatrics

Year:

2009

Language:

english

File:

PDF, 173 KB

english, 2009

9

A comparison of conventional and molecular microbiology in detecting differences in pneumococcal colonization in healthy children and children with upper respiratory illness

Masashi Ogami, Muneki Hotomi, Akihisa Togawa, Noboru Yamanaka

Journal:

European Journal of Pediatrics

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

10

Macrolide-resistant genes ofStreptococcus pyogenesisolated from the upper respiratory tract by polymerase chain reaction

Dewan S. Billal, Muneki Hotomi, Kazuma Yamauchi, Keiji Fujihara, Shinji Tamura, Kiyonori Kuki, Rinya Sugita, Miyoko Endou, Jun Mukaigawa, Noboru Yamanaka

Journal:

Journal of Infection and Chemotherapy

Year:

2004

Language:

english

File:

PDF, 310 KB

english, 2004

11

Clinical bacteriology and immunology in acute otitis media in children

Noboru Yamanaka, Muneki Hotomi, Dewan S. Billal

Journal:

Journal of Infection and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 514 KB

english, 2008

12

Protection against systemic fatal pneumococcal infection by maternal intranasal immunization with pneumococcal surface protein A (PspA)

Toshiki Katsurahara, Muneki Hotomi, Kazuma Yamauchi, Dewan S. Billal, Noboru Yamanaka

Journal:

Journal of Infection and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

13

Distribution of fibronectin-binding protein genes (prtF1andprtF2) and streptococcal pyrogenic exotoxin genes (spe) amongStreptococcus pyogenesin Japan

Muneki Hotomi, Dewan S. Billal, Akihisa Togawa, Yorihiko Ikeda, Shin Takei, Masamitsu Kono, Masahi Ogami, Kimiko Ubukata, Rinya Sugita, Keiji Fujihara, Noboru Yamanaka

Journal:

Journal of Infection and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

14

T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas

Levent Bekir Beder, Mehmet Gunduz, Muneki Hotomi, Keiji Fujihara, Jun Shimada, Shinji Tamura, Esra Gunduz, Kunihiro Fukushima, Kursat Yaykasli, Reidar Grenman, Kenji Shimizu, Noboru Yamanaka

Journal:

Year:

2009

Language:

english

File:

PDF, 1.16 MB

english, 2009

15

Immunological Deficiency in “Otitis-prone” Children

NOBORU YAMANAKA, MUNEKI HOTOMI, JUN SHIMADA, AKIHITO TOGAWA

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 644 KB

english, 1997

16

Increase of Macrolide-Resistant Streptococcus pneumoniae-Expressing mefE or ermB Gene in the Nasopharynx among Children with Otitis Media

Muneki Hotomi, Dewan S. Billal, Jun Shimada, Masaki Suzumoto, Kazuma Yamauchi, Keiji Fujihara, Noboru Yamanaka

Journal:

The Laryngoscope

Year:

2005

Language:

english

File:

PDF, 336 KB

english, 2005

17

A Novel Definition of Extrathyroidal Invasion for Patients with Papillary Thyroid Carcinoma for Predicting Prognosis

Hotomi, Muneki, Sugitani, Iwao, Toda, Kazuhisa, Kawabata, Kazuyoshi, Fujimoto, Yoshihide

Journal:

World Journal of Surgery

Year:

2012

Language:

english

File:

PDF, 257 KB

english, 2012

18

P-glycoprotein expression in human major and minor salivary glands

Takashi Uematsu, Minoru Yamaoka, Takashi Matsuura, Ryosuke Doto, Hirohito Hotomi, Aki-Sato Yamada, Yoko Hasumi-Nakayama, Daisuke Kayamoto

Journal:

Archives of Oral Biology

Year:

2001

Language:

english

File:

PDF, 593 KB

english, 2001

19

Formation of biofilm by Haemophilus influenzae isolated from pediatric intractable otitis media

Satomi Moriyama, Muneki Hotomi, Jun Shimada, Dewan S. Billal, Keiji Fujihara, Noboru Yamanaka

Journal:

Auris Nasus Larynx

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

20

A scoring system for management of acute pharyngo-tonsillitis in adults

Masaki Suzumoto, Muneki Hotomi, Dewan S. Billal, Keiji Fujihara, Yasuaki Harabuchi, Noboru Yamanaka

Journal:

Auris Nasus Larynx

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

21

Pathogenic role of tonsillar lymphocytes in associated with HSP60/65 in Pustulosis Palmaris et Plantaris

Masaki Hayashi, Keiji Fujihara, Levent B. Beder, Yoshikazu Yamamoto, Muneki Hotomi, Noboru Yamanaka

Journal:

Auris Nasus Larynx

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

22

Nontypeable Haemophilus influenzae isolated from intractable acute otitis media internalized into cultured human epithelial cells

Muneki Hotomi, Jun Arai, Dewan S. Billal, Shin Takei, Yorihiko Ikeda, Masashi Ogami, Masamitsu Kono, Levent B. Beder, Kazuo Toya, Michio Kimura, Noboru Yamanaka

Journal:

Auris Nasus Larynx

Year:

2010

Language:

english

File:

PDF, 946 KB

english, 2010

23

Haemophilus influenzae and Haemophilus haemolyticus in tonsillar cultures of adults with acute pharyngotonsillitis

Muneki Hotomi, Masamitsu Kono, Akihisa Togawa, Jun Arai, Shin Takei, Yorihiko Ikeda, Masashi Ogami, Timothy F. Murphy, Noboru Yamanaka

Journal:

Auris Nasus Larynx

Year:

2010

Language:

english

File:

PDF, 200 KB

english, 2010

24

Loss of erythromycin resistance genes from strains of Streptococcus pyogenes that have developed resistance to levofloxacin

Dewan Sakhawat Billal, Muneki Hotomi, Steve S. Yan, Daniel P. Fedorko, Jun Shimada, Keiji Fujihara, Noboru Yamanaka

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

25

Tonsillitis index: An objective tool for quantifying the indications for tonsillectomy for recurrent acute tonsillitis

Keiji Fujihara, Hironobu Goto, Masanobu Hiraoka, Masaki Hayashi, Muneki Hotomi, Shinji Tamura, Kiyonori Kuki, Noboru Yamanaka, Peter J. Koltai

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

26

Clonal spread of β-lactamase-producing amoxicillin–clavulanate-resistant (BLPACR) strains of non-typeable Haemophilus influenzae among young children attending a day care in Japan

Makoto Ito, Muneki Hotomi, Yumiko Maruyama, Miyako Hatano, Hisashi Sugimoto, Tomokazu Yoshizaki, Noboru Yamanaka

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

27

A recombinant P4 protein of Haemophilus influenzae induces specific immune responses biologically active against nasopharyngeal colonization in mice after intranasal immunization

Muneki Hotomi, Yorihiko Ikeda, Masaki Suzumoto, Kazuma Yamauchi, Bruce A. Green, Gary Zlotnick, Dewan S. Billal, Jun Shimada, Keiji Fujihara, Noboru Yamanaka

Journal:

Year:

2005

Language:

english

File:

PDF, 136 KB

english, 2005

28

Maternal intranasal immunization with outer membrane protein P6 maintains specific antibody level of derived offspring

Kazuma Yamauchi, Muneki Hotomi, Dewan S. Billal, Masaki Suzumoto, Noboru Yamanaka

Journal:

Year:

2006

Language:

english

File:

PDF, 171 KB

english, 2006

29

Efficacy of a novel oral carbapenem, tebipenem pivoxil (TBM-PI), against experimental otitis media caused by penicillin resistant Streptococcus pneumoniae in chinchilla

Muneki Hotomi, Masaki Suzumoto, Koju Itahashi, Jun Nagura, Takayoshi Fukushima, Jun Shimada, Dewan S. Billal, Kazuma Yamauchi, Keiji Fujihara, Noboru Yamanaka

Journal:

Year:

2007

Language:

english

File:

PDF, 802 KB

english, 2007

30

Rotavirus vaccine for developing countries

Dewan Sakhawat Billal, Muneki Hotomi, Noboru Yamanaka

Journal:

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

31

Wealth and child survival: India and Bangladesh

Dewan Sakhawat Billal, Muneki Hotomi, Noboru Yamanaka

Journal:

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

32

Intermittent preventive treatment with antimalarial drugs

Dewan Sakhawat Billal, Muneki Hotomi, Noboru Yamanaka

Journal:

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

33

Intranasal immunization with recombinant outer membrane protein P6 induces specific immune responses against nontypeable Haemophilus influenzae

Muneki Hotomi, Noboru Yamanaka, Jun Shimada, Masaki Suzumoto, Yorihiko Ikeda, Akihiro Sakai, Jun Arai, Bruce Green

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

34

Specific mucosal immunity and enhanced nasopharyngeal clearance of nontypeable Haemophilus influenzae after intranasal immunization with outer membrane protein P6 and cholera toxin

Muneki Hotomi, Tadahito Saito, Noboru Yamanaka

Journal:

Year:

1998

Language:

english

File:

PDF, 896 KB

english, 1998

35

Squamous cell carcinoma arising in a Warthin’s tumor

Mehmet Gunduz, Noboru Yamanaka, Muneki Hotomi, Kiyonori Kuki, Michiaki Yokoyama, Hirokazu Nakamine

Journal:

Auris Nasus Larynx

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

36

Tonsil—a mysterious organ-novel approaches using human skin/SCID chimera

Noboru Yamanaka, Yoshikazu Yamamoto, Muneki Hotomi, Masaki Suzumoto, Keiji Fujihara, Kiyonori Kuki

Journal:

International Congress Series

Year:

2003

Language:

english

File:

PDF, 381 KB

english, 2003

37

Immunological derangement in tonsils with recurrent infections: A study of co-stimulatory factors on tonsillar B lymphocytes

Keiji Fujihara, Hironobu Goto, Muneki Hotomi, Masami Kobayashi, Masaki Hayashi, Shinji Tamura, Kiyonori Kuki, Noboru Yamanaka

Journal:

International Congress Series

Year:

2003

Language:

english

File:

PDF, 117 KB

english, 2003

38

Detection of Haemophilus influenzae in middle ear of otitis media with effusion by polymerase chain reaction

Muneki Hotomi, Toshihide Tabata, Hiromu Kakiuchi, Masaru Kunimoto

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

1993

Language:

english

File:

PDF, 570 KB

english, 1993

39

P746 Bacteriological efficacy of azithromycin on non-typeable Haemophilus infiuenzae adhered to and entered cultured human epithelial cells

N. Yamanaka, M. Hotomi, K. Fujihara, S. Tamura, T. Tomita, S. Saito

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

40

Minimal biofilm eradication concentration of antimicrobial agents against nontypeableHaemophilus influenzaeisolated from middle ear fluids of intractable acute otitis media

Takei, Shin, Hotomi, Muneki, Yamanaka, Noboru

Journal:

Journal of Infection and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 349 KB

english, 2013

41

SP25-1 Why have the upper respiratory infections become intractable? – Battle of the bacteria and the host defense mechanism

Hotomi, M., Yamanaka, N.

Journal:

International Journal of Antimicrobial Agents

Year:

2013

Language:

english

File:

PDF, 63 KB

english, 2013

42

Immunological study of adenoid and nasopharynx

Hotomi, Muneki, Kuki, Kiyonori, Tamura, Shinji, Yamanaka, Noboru

Journal:

Pathophysiology

Year:

1994

Language:

english

File:

PDF, 68 KB

english, 1994

43

Genetic characteristics of Haemophilus influenzae and Streptococcus pneumoniae isolated from children with conjunctivitis-otitis media syndrome

Sugita, Gen, Hotomi, Muneki, Sugita, Rinya, Kono, Masamitsu, Togawa, Akihisa, Yamauchi, Kazuma, Funaki, Toshinari, Yamanaka, Noboru

Journal:

Journal of Infection and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 234 KB

english, 2014

44

Antimicrobial resistance in Haemophilus influenzae isolated from the nasopharynx among Japanese children with acute otitis media

Hotomi, Muneki, Sakai, Keiji Fujihara Akihiro, Billal, Dewan S., Shimada, Jun, Suzumoto, Masaki, Yamanaka, Noboru

Journal:

Acta Oto-Laryngologica

Year:

2006

Language:

english

File:

PDF, 176 KB

english, 2006

45

Functions of tonsils in the mucosal immune system of the upper respiratory tract using a novel animal model, Suncus murinus

Suzumoto, Masaki, Hotomi, Muneki, Fujihara, Keiji, Tamura, Shinji, Kuki, Kiyonori, Tohya, Kazuo, Kimura, Michio, Yamanaka, Noboru

Journal:

Acta Oto-Laryngologica

Year:

2006

Language:

english

File:

PDF, 355 KB

english, 2006

46

Practical guideline for management of acute rhinosinusitis in Japan

Yamanaka, Noboru, Iino, Yukiko, Uno, Yoshifumi, Kudo, Fumiyo, Kurono, Yuichi, Suzaki, Harumi, Haruna, Shinichi, Hotomi, Muneki, Horiguchi, Shigetoshi, Mashima, Yuichi, Matsubara, Shigenori, Nakayama,

Journal:

Auris Nasus Larynx

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

47

PIR-B-Deficient Mice Are Susceptible to Salmonella Infection

Torii, I., Oka, S., Hotomi, M., Benjamin, W. H., Takai, T., Kearney, J. F., Briles, D. E., Kubagawa, H.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 506 KB

english, 2008

48

Prevalence of Streptococcus Invasive Locus (sil) and Its Relationship with Macrolide Resistance among Group A Streptococcus Strains

Billal, D. S., Hotomi, M., Shimada, J., Fujihara, K., Ubukata, K., Sugita, R., Yamanaka, N.

Journal:

Journal of Clinical Microbiology

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

49

Genetic Characteristics and Clonal Dissemination of -Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae Strains Isolated from the Upper Respiratory Tract of Patients in Japan

Hotomi, M., Fujihara, K., Billal, D. S., Suzuki, K., Nishimura, T., Baba, S., Yamanaka, N.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

50

Factors Associated with Clinical Outcomes in Acute Otitis Media

Hotomi, M., Yamanaka, N., Ikeda, Y., Shimada, J., Faden, H.

Journal:

Annals of Otology, Rhinology & Laryngology

Year:

2004

Language:

english

File:

PDF, 758 KB

english, 2004

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